NRP1 antagonist 1

Modify Date: 2025-12-02 19:19:31

NRP1 antagonist 1 Structure
NRP1 antagonist 1 structure
Common Name NRP1 antagonist 1
CAS Number 2569598-01-0 Molecular Weight 450.58
Density N/A Boiling Point N/A
Molecular Formula C22H22N6OS2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NRP1 antagonist 1


NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].

 Names

Name NRP1 antagonist 1

 NRP1 antagonist 1 Biological Activity

Description NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].
Related Catalog
References

[1]. Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28(1):115183.

 Chemical & Physical Properties

Molecular Formula C22H22N6OS2
Molecular Weight 450.58
InChIKey OWXHHEPYWMHKHC-UHFFFAOYSA-N
SMILES CCc1nnc(NC(=O)CSc2nnc(-c3ccc(C)cc3)n2-c2cccc(C)c2)s1
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