oleoylglycine

Modify Date: 2025-08-25 18:33:45

oleoylglycine Structure
oleoylglycine structure
Common Name oleoylglycine
CAS Number 2601-90-3 Molecular Weight 339.513
Density 1.0±0.1 g/cm3 Boiling Point 525.6±43.0 °C at 760 mmHg
Molecular Formula C20H37NO3 Melting Point N/A
MSDS Chinese USA Flash Point 271.7±28.2 °C

 Use of oleoylglycine


N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

 Names

Name N-Oleoylglycine
Synonym More Synonyms

 oleoylglycine Biological Activity

Description N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.
Related Catalog
Target

Human Endogenous Metabolite

CB1 Receptor

Akt

In Vitro N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. N-Oleoyl glycine (1, 5, 10, 20, 50 μM) dose- and time-dependently stimulates 3T3-L1 adipogenesis after treatment for 1-10 days via activation of CB1R. N-Oleoyl glycine also elevates Akt signaling pathway during the differentiation of 3T3-L1 adipocytes[1].
References

[1]. Wang S, et al. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2015 Oct 23;466(3):438-43.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 525.6±43.0 °C at 760 mmHg
Molecular Formula C20H37NO3
Molecular Weight 339.513
Flash Point 271.7±28.2 °C
Exact Mass 339.277344
PSA 66.40000
LogP 6.57
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.478
InChIKey HPFXACZRFJDURI-KTKRTIGZSA-N
SMILES CCCCCCCCC=CCCCCCCCC(=O)NCC(=O)O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 oleoylglycineBioassay

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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed a...
Source: ChEMBL
Target: Sodium- and chloride-dependent glycine transporter 2
External Id: CHEMBL4481231
Name: Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed a...
Source: ChEMBL
Target: Sodium- and chloride-dependent glycine transporter 2
External Id: CHEMBL4481230
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: Antiinflammatory activity against IFN-gamma-stimulated human HaCaT cells assessed as ...
Source: ChEMBL
Target: HaCaT
External Id: CHEMBL1674456
Name: Stabilization of p53 in human papillomavirus-positive cells
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Cellular tumor antigen p53
External Id: HMS1485
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu...
Source: 15621
Target: G protein-activated inward rectifier potassium channel 2
External Id: VANDERBILT_HTS_GIRK2_MPD
Name: Cytotoxicity against human HaCaT cells at 50 to 100 uM after 24 hrs by MTT assay
Source: ChEMBL
Target: HaCaT
External Id: CHEMBL1674457
Name: Degradation half life in human plasma at 1000 ng/ml by LC-MS/MS analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL4481223
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 Synonyms

N-(1-Oxo-9-octadecenyl)-(Z)-glycine
N-[(9Z)-9-Octadecenoyl]glycine
oleoylglycine
N-Oleoylglycine
N-[(9Z)-Octadec-9-enoyl]glycine
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