SC 22716 structure
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Common Name | SC 22716 | ||
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CAS Number | 262451-89-8 | Molecular Weight | 267.36500 | |
Density | 1.065g/cm3 | Boiling Point | 418.5ºC at 760 mmHg | |
Molecular Formula | C18H21NO | Melting Point | N/A | |
MSDS | USA | Flash Point | 122.8ºC |
Use of SC 22716SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis[1]. |
Name | 1-[2-(4-phenylphenoxy)ethyl]pyrrolidine |
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Synonym | More Synonyms |
Description | SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis[1]. |
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Related Catalog | |
References |
Density | 1.065g/cm3 |
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Boiling Point | 418.5ºC at 760 mmHg |
Molecular Formula | C18H21NO |
Molecular Weight | 267.36500 |
Flash Point | 122.8ºC |
Exact Mass | 267.16200 |
PSA | 12.47000 |
LogP | 3.76610 |
Vapour Pressure | 3.27E-07mmHg at 25°C |
Index of Refraction | 1.568 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
~% SC 22716 CAS#:262451-89-8 |
Literature: Penning, Thomas D.; Chandrakumar, Nizal S.; Chen, Barbara B.; Chen, Helen Y.; Desai, Bipin N.; Djuric, Stevan W.; Docter, Stephen H.; Gasiecki, Alan F.; Haack, Richard A.; Miyashiro, Julie M.; Russell, Mark A.; Yu, Stella S.; Corley, David G.; Durley, Richard C.; Kilpatrick, Brian F.; Parnas, Barry L.; Askonas, Leslie J.; Gierse, James K.; Harding, Elizabeth I.; Highkin, Maureen K.; Kachur, James F.; Kim, Suzanne H.; Krivi, Gwen G.; Villani-Price, Doreen; Pyla, E. Yvonne; Smith, Walter G.; Ghoreishi-Haack, Nayereh S. Journal of Medicinal Chemistry, 2000 , vol. 43, # 4 p. 721 - 735 |
~% SC 22716 CAS#:262451-89-8 |
Literature: Adir et Compagnie Patent: US6339092 B1, 2002 ; Location in patent: Page column 5 ; |
Precursor 3 | |
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DownStream 0 |
1-[2-(biphenyloxy)ethyl]pyrrolidine |
1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine |