ZK824190 hydrochloride
Modify Date: 2025-08-26 18:03:47
ZK824190 hydrochloride structure
|
Common Name | ZK824190 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2629177-12-2 | Molecular Weight | 450.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H21ClF2N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZK824190 hydrochlorideZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively[1]. |
| Name | ZK824190 hydrochloride |
|---|
| Description | ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively[1]. |
|---|---|
| Related Catalog | |
| In Vivo | ZK824190 (2 mg/kg; PO; Rats with EAE model) exhibits a relatively high oral availability and a moderate half time (T1/2=2.8 h)[1]. |
| References |
| Molecular Formula | C22H21ClF2N2O4 |
|---|---|
| Molecular Weight | 450.86 |