DDO-6600
Modify Date: 2024-01-07 09:35:14
DDO-6600 structure
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Common Name | DDO-6600 | ||
|---|---|---|---|---|
| CAS Number | 2640292-37-9 | Molecular Weight | 428.536 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H28N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DDO-6600DDO-6600 (DDO 6600) is a potent, selective, covalent inhibitor of Hsp90, covalently modifies Cys598 on Hsp90 and disrupts the interaction between Hsp90 and Cdc37 (IC50=6.67 uM).DDO-6600 exhibited antiproliferative activities against multiple tumor cells without inhibiting ATPase activity.DDO-6600 induced the degradation of kinase client proteins in multiple tumor cell lines, promoted apoptosis, and inhibited cell motility.DDO-6600 exhibits antitumor activity in HCT-116 mouse models. |
| Name | DDO-6600 |
|---|
| Description | DDO-6600 (DDO 6600) is a potent, selective, covalent inhibitor of Hsp90, covalently modifies Cys598 on Hsp90 and disrupts the interaction between Hsp90 and Cdc37 (IC50=6.67 uM).DDO-6600 exhibited antiproliferative activities against multiple tumor cells without inhibiting ATPase activity.DDO-6600 induced the degradation of kinase client proteins in multiple tumor cell lines, promoted apoptosis, and inhibited cell motility.DDO-6600 exhibits antitumor activity in HCT-116 mouse models. |
|---|---|
| References | 1. Li Li, et al. Cell Chem Biol. 2021 Oct 21;28(10):1446-1459.e6. |
| Molecular Formula | C26H28N4O2 |
|---|---|
| Molecular Weight | 428.536 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: DDO-6600
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: DDO-6600
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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