DDO-7263
Modify Date: 2025-08-27 07:08:02
DDO-7263 structure
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Common Name | DDO-7263 | ||
|---|---|---|---|---|
| CAS Number | 2254004-96-9 | Molecular Weight | 273.24 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H9F2N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DDO-7263DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2 activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity[1]. |
| Name | DDO-7263 |
|---|
| Description | DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2 activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C14H9F2N3O |
|---|---|
| Molecular Weight | 273.24 |
| InChIKey | HITVBBDLWZDVIV-UHFFFAOYSA-N |
| SMILES | Cc1ccc(-c2noc(-c3ccc(F)c(F)c3)n2)cn1 |