DDO-7263

Modify Date: 2024-01-09 00:49:53

DDO-7263 structure	Common Name	DDO-7263
	CAS Number	2254004-96-9	Molecular Weight	273.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₉F₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DDO-7263

DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2 activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity[1].

Name	DDO-7263

Description	DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2 activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Inflammation/Immunology
References	[1]. Zhen Dai, et al. Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome. J Med Chem. 2022 Mar 24;65(6):5029-5043.

Molecular Formula	C₁₄H₉F₂N₃O
Molecular Weight	273.24

DC Chemicals Limited
China
Product Name: DDO-7263
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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DDO-7263 Biological Activity

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