STAT3-IN-18
STAT3-IN-18 structure
|
Common Name | STAT3-IN-18 | ||
|---|---|---|---|---|
| CAS Number | 2668267-41-0 | Molecular Weight | 630.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H24Cl2N2O6Pt | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STAT3-IN-18STAT3-IN-18 (compound SPP) is a platinum (IV) complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo. |
| Name | STAT3-IN-18 |
|---|
| Description | STAT3-IN-18 (compound SPP) is a platinum (IV) complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C18H24Cl2N2O6Pt |
|---|---|
| Molecular Weight | 630.38 |