Levomefolic acid-13C5

Modify Date: 2024-04-06 17:12:30

Levomefolic acid-13C5 Structure
Levomefolic acid-13C5 structure
Common Name Levomefolic acid-13C5
CAS Number 2687960-08-1 Molecular Weight 464.42
Density N/A Boiling Point N/A
Molecular Formula C1513C5H25N7O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Levomefolic acid-13C5


Levomefolic acid-13C5 is the 13C labeled Levomefolic acid[1]. Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].

 Names

Name Levomefolic acid-13C5

 Levomefolic acid-13C5 Biological Activity

Description Levomefolic acid-13C5 is the 13C labeled Levomefolic acid[1]. Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Manisha Prajapat, et al. Virtual screening and molecular dynamics study of approved drugs as inhibitors of spike protein S1 domain and ACE2 interaction in SARS-CoV-2. J Mol Graph Model. 2020 Dec;101:107716.  

[3]. Maša Vidmar Golja, et al. Simultaneous quantification of intracellular concentrations of clinically important metabolites of folate-homocysteine cycle by LC-MS/MS. Anal Biochem. 2020 Sep 15;605:113830.  

 Chemical & Physical Properties

Molecular Formula C1513C5H25N7O6
Molecular Weight 464.42