RAF-IN-1
Modify Date: 2025-08-26 20:59:35
RAF-IN-1 structure
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Common Name | RAF-IN-1 | ||
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| CAS Number | 2695505-82-7 | Molecular Weight | 497.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H22F3N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RAF-IN-1RAF-IN-1 is a potent b/cRAF inhibitor with an IC50s of 3.8 nM, 36 nM, 29.4 nM for cRAF, bRAFwt, and bRAFV600E. RAF-IN-1 shows cell growth inhibition with GI50s of 3.4 and 2.9 nM for H358 and A375 cell line bearing bRAFV600E mutation, respectively[1]. |
| Name | RAF-IN-1 |
|---|
| Description | RAF-IN-1 is a potent b/cRAF inhibitor with an IC50s of 3.8 nM, 36 nM, 29.4 nM for cRAF, bRAFwt, and bRAFV600E. RAF-IN-1 shows cell growth inhibition with GI50s of 3.4 and 2.9 nM for H358 and A375 cell line bearing bRAFV600E mutation, respectively[1]. |
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| Related Catalog | |
| Target |
BRafV600E:29.4 nM (IC50) BRAFWT:36 nM (IC50) c-Raf:3.8 nM (IC50) |
| References |
| Molecular Formula | C26H22F3N3O4 |
|---|---|
| Molecular Weight | 497.47 |