EPZ-719

Modify Date: 2025-09-03 14:36:13

EPZ-719 Structure
EPZ-719 structure
Common Name EPZ-719
CAS Number 2697176-16-0 Molecular Weight 450.57
Density N/A Boiling Point N/A
Molecular Formula C22H31FN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EPZ-719


EPZ-719 is a novel and potent SETD2 inhibitor ( IC50 = 0.005 μM) with a high selectivity over other histone methyltransferases.

 Names

Name EPZ-719

 EPZ-719 Biological Activity

Description EPZ-719 is a novel and potent SETD2 inhibitor ( IC50 = 0.005 μM) with a high selectivity over other histone methyltransferases.
Related Catalog
References

[1]. Lampe JW, et al. Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies. ACS Med Chem Lett. 2021 Aug 24;12(10):1539-1545.

 Chemical & Physical Properties

Molecular Formula C22H31FN4O3S
Molecular Weight 450.57
InChIKey ZLVKIBLQXFILMA-IKGGRYGDSA-N
SMILES Cc1ccc(F)c2cc(C(=O)NC3CCCC(N4CCC(N(C)S(C)(=O)=O)C4)C3)[nH]c12
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