2'-Methoxykurarinone
Modify Date: 2024-01-10 09:08:37
2'-Methoxykurarinone structure
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Common Name | 2'-Methoxykurarinone | ||
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| CAS Number | 270249-38-2 | Molecular Weight | 452.539 | |
| Density | 1.171±0.06 g/cm3 (20 ºC 760 Torr) | Boiling Point | 643.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C27H32O6 | Melting Point | 112-115 ºC | |
| MSDS | N/A | Flash Point | 213.2±25.0 °C | |
Use of 2'-Methoxykurarinone(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells[1][2]. |
| Name | 2'-O-Methylkurarinone |
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| Synonym | More Synonyms |
| Description | (2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.171±0.06 g/cm3 (20 ºC 760 Torr) |
|---|---|
| Boiling Point | 643.6±55.0 °C at 760 mmHg |
| Melting Point | 112-115 ºC |
| Molecular Formula | C27H32O6 |
| Molecular Weight | 452.539 |
| Flash Point | 213.2±25.0 °C |
| Exact Mass | 452.219879 |
| PSA | 85.22000 |
| LogP | 7.05 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.575 |
| Water Solubility | Insuluble (2.6E-4 g/L) (25 ºC) |
| Hazard Codes | Xi |
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| 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- |
| (2S)-7-Hydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-5-methoxy-2,3-dihydro-4H-chromen-4-one |
| Kurarinone, 2'-O-methyl- |
| 2'-Methoxykurarinone |