SARS-CoV-2-IN-22

Modify Date: 2024-01-10 17:08:34

SARS-CoV-2-IN-22 structure	Common Name	SARS-CoV-2-IN-22
	CAS Number	2710278-53-6	Molecular Weight	456.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₄N₂O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SARS-CoV-2-IN-22

SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus entry inhibitor with an IC50 value of 16.96 µM[1].

Name	SARS-CoV-2-IN-22

Description	SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus entry inhibitor with an IC50 value of 16.96 µM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 16.96 µM (SARS-CoV-2)[1]
In Vitro	SARS-CoV-2-IN-22 (Compound 9a) effectively blocks the binding of SARS-CoV-2 to the host ACE2 receptor through dual recognition of SARS-CoV-2 spike receptor-binding domain (RBD) and human ACE2. SARS-CoV-2-IN-2 displays no cytotoxicity to normal cells (LO2)[1].
References	[1]. Ting Xu, et al. Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors. Bioorg Med Chem. 2022 Aug 1;67:116838.

Molecular Formula	C₂₇H₂₄N₂O₃S
Molecular Weight	456.56