Antimalarial agent 15

Modify Date: 2024-01-12 11:13:42

Antimalarial agent 15 structure	Common Name	Antimalarial agent 15
	CAS Number	956928-33-9	Molecular Weight	502.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₀N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antimalarial agent 15

Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].

Name	Antimalarial agent 15

Description	Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	IC50: 20 nM (P. falciparum 3D7)[1]
In Vitro	Antimalarial agent 15 shows no cytotoxicity against mammalian cells or affects the growth of bacteria and fungi up to 30 μM[1].
References	[1]. Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.

Molecular Formula	C₂₉H₃₀N₂O₆
Molecular Weight	502.56