fthalide

Modify Date: 2025-08-26 04:17:08

fthalide structure	Common Name	fthalide
	CAS Number	27355-22-2	Molecular Weight	271.912
	Density	1.8±0.1 g/cm3	Boiling Point	464.4±45.0 °C at 760 mmHg
	Molecular Formula	C₈H₂Cl₄O₂	Melting Point	209-210ºC
	MSDS	Chinese	Flash Point	215.8±27.7 °C

Name	4,5,6,7-tetrachloro-2-benzofuran-1(3H)-one
Synonym	More Synonyms

Density	1.8±0.1 g/cm3
Boiling Point	464.4±45.0 °C at 760 mmHg
Melting Point	209-210ºC
Molecular Formula	C₈H₂Cl₄O₂
Molecular Weight	271.912
Flash Point	215.8±27.7 °C
Exact Mass	269.880890
PSA	26.30000
LogP	2.73
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.636

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI3870000

CHEMICAL NAME :: Phthalide, 4,5,6,7-tetrachloro-

CAS REGISTRY NUMBER :: 27355-22-2

BEILSTEIN REFERENCE NO. :: 0182477

LAST UPDATED :: 199612

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C8-H2-Cl4-O2

MOLECULAR WEIGHT :: 271.90

WISWESSER LINE NOTATION :: T56 BVO DHJ FG GG HG IG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 4,73,1976/1977

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4100 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 15,311,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (40),32,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (36),32,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 273 gm/kg/13W-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 15,311,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2190 gm/kg/2Y-C

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 15,311,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 546 gm/kg/13W-C

TOXIC EFFECTS :: Liver - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 15,311,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4380 gm/kg/2Y-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 15,311,1990

Hazard Codes	Xi
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36-S24/25
WGK Germany	3
HS Code	2932209013

Tetrachlorophth...

CAS#:117-08-8

~87%

fthalide

CAS#:27355-22-2

Literature: Narasimhan, Srinivasan Heterocycles, 1982 , vol. 18, p. 131 - 135

Phthalic anhydride

CAS#:85-44-9

fthalide

CAS#:27355-22-2

Literature: Graebe Justus Liebigs Annalen der Chemie, 1887 , vol. 238, p. 326,327 Chemische Berichte, 1883 , vol. 16, p. 861

thf

CAS#:109-99-9

Tetrachlorophth...

CAS#:117-08-8

fthalide

CAS#:27355-22-2

Literature: Parrini Gazzetta Chimica Italiana, 1957 , vol. 87, p. 1147,1156

Diethyl ether

CAS#:60-29-7

Tetrachlorophth...

CAS#:117-08-8

fthalide

CAS#:27355-22-2

Literature: Parrini Gazzetta Chimica Italiana, 1957 , vol. 87, p. 1147,1156

Tetrachlorophth...

CAS#:117-08-8

acetic acid

CAS#:64-19-7

fthalide

CAS#:27355-22-2

Literature: Graebe Justus Liebigs Annalen der Chemie, 1887 , vol. 238, p. 326,327 Chemische Berichte, 1883 , vol. 16, p. 861

Precursor 5
CAS#:117-08-8 Tetrachlorophth... CAS#:85-44-9 Phthalic anhydride CAS#:109-99-9 thf CAS#:60-29-7 Diethyl ether
CAS#:64-19-7 acetic acid
DownStream 0

HS Code	2932209013
Summary	2932209013 4,5,6,7-tetrachloroisobenzofuran-1(3h)-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:6.5%。general tariff:20.0%

4,5,6,7-TETRACHLORO-PHTHALIDE

Rabcide

1(3H)-4,5,6,7-tetrachloroisobenzofuranone

EINECS 229-405-2

fthalide

Phthalide,4,5,6,7-tetrachloro

4,5,6,7-Tetrachloro-1(3H)-isobenzofuranone (9CI)

phthalide

1(3H)-Isobenzofuranone, 4,5,6,7-tetrachloro-

4,5,6,7-Tetrachloro-2-benzofuran-1(3H)-one

KF-32

PHH

4,5,6,7-tetrachloroisobenzofuran-1(3H)-one

4,5,6,7-tetrachloro-1(3H)-isobenzofuranone

4,5,6,7-tetrachloro-3H-2-benzofuran-1-one

4,5,6,7-Tetrachlor-phthalid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: fthalide
Price: Check
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: fthalide
Price: ￥808.0/10mg
Purity: 98.0%
Delivery: Inquiry
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fthalide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.