TNIK-IN-4

Modify Date: 2024-04-06 11:07:55

TNIK-IN-4 structure	Common Name	TNIK-IN-4
	CAS Number	2754266-04-9	Molecular Weight	365.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₆FN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TNIK-IN-4

TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116[1].

Name	TNIK-IN-4

Description	TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 0.61 μM (TNIK)[1]
In Vitro	TNIK-IN-4 (compound 5a) (0.4-100 μM; 72 hours) has inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM[1]. Cell Proliferation Assay Cell Line: HCT116 cells[1] Concentration: 0.4, 1.2, 3.7, 11.1, 33.3 and 100 μM Incubation Time: 72 hours Result: Showed inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM.
References	[1]. Luo X, Yang R, Li Y, Zhang L, Yang S, Li L. Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer. Bioorg Med Chem Lett. 2022;67:128745.

Molecular Formula	C₂₀H₁₆FN₃O₃
Molecular Weight	365.36

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com