TNIK-IN-2

Modify Date: 2024-09-23 16:41:40

TNIK-IN-2 Structure
TNIK-IN-2 structure
Common Name TNIK-IN-2
CAS Number 2754265-76-2 Molecular Weight 373.40
Density N/A Boiling Point N/A
Molecular Formula C22H19N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNIK-IN-2


TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].

 Names

Name TNIK-IN-2

 TNIK-IN-2 Biological Activity

Description TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].
Related Catalog
Target

IC50: 1.3337 μM (TNIK)[1]

In Vitro TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells[1].
References

[1]. Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5(2 H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5.

 Chemical & Physical Properties

Molecular Formula C22H19N3O3
Molecular Weight 373.40
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