DC Chemicals Limited
China
Product Name: TNIK-IN-2
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Purity: 98.0%
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Contact: Tony Cao

2754265-76-2

2754265-76-2 structure

2754265-76-2 structure

Name: TNIK-IN-2
Chemical Name: TNIK-IN-2
CAS Number: 2754265-76-2
Molecular Formula: C₂₂H₁₉N₃O₃
Molecular Weight: 373.40
Catalog: Research Areas Cancer
Create Date: 2022-04-01 12:09:11
Modify Date: 2023-01-15 09:20:46
TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].

Name	TNIK-IN-2

Description	TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 1.3337 μM (TNIK)[1]
In Vitro	TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells[1].
References	[1]. Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5(2 H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5.

Molecular Formula	C₂₂H₁₉N₃O₃
Molecular Weight	373.40