Mab Aspartate Decarboxylase-IN-1
Modify Date: 2024-01-29 14:42:30
Mab Aspartate Decarboxylase-IN-1 structure
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Common Name | Mab Aspartate Decarboxylase-IN-1 | ||
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| CAS Number | 2755712-12-8 | Molecular Weight | 293.28 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H11N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mab Aspartate Decarboxylase-IN-1Mab Aspartate Decarboxylase-IN-1 is a potent aspartate decarboxylase (PanD) inhibitor with an IC50 value of 56.3 µM. Mab Aspartate Decarboxylase-IN-1 shows antibacterial activity[1]. |
| Name | Mab Aspartate Decarboxylase-IN-1 |
|---|
| Description | Mab Aspartate Decarboxylase-IN-1 is a potent aspartate decarboxylase (PanD) inhibitor with an IC50 value of 56.3 µM. Mab Aspartate Decarboxylase-IN-1 shows antibacterial activity[1]. |
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| Related Catalog | |
| Target |
IC50: 56.3 µM (aspartate decarboxylase (PanD))[1]. |
| In Vitro | Mab Aspartate Decarboxylase-IN-1 (compound analogue 2) shows inhibits against the mutants Mab PanDE119A, Mab PanDS135A and Mab PanDY126A mutants with the inhibition rates of 70.5%, 74.4%, 81.8%, respectively[1]. Mab Aspartate Decarboxylase-IN-1 (0-200 µM) shows inhibition on mycobacterium abscessus (Mab) PanD enzyme activity in the conversion of l-Asp to β-Ala with an IC50 value of 56.3±4.8 µM[1]. Mab Aspartate Decarboxylase-IN-1 (0-4 mM) shows antibacterial activity for M. abscessus subsp. abscessus ATCC 19977 with an IC50 value of 0.7mM, and M. abscessus subsp. bolletii CCUG 50184T, M. abscessus subsp. massiliense CCUG 48898T, M. abscessus subsp. abscessus Bamboo, M. abscessus subsp. abscessus ATCC 19977 with IC50s of 1-2 mM[1]. Mab Aspartate Decarboxylase-IN-1 shows mainly electrostatic- and hydrogen bonding interaction with the target enzyme[1]. |
| References |
| Molecular Formula | C16H11N3O3 |
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| Molecular Weight | 293.28 |