PDGFRα/FLT3-ITD-IN-1

Modify Date: 2024-04-12 19:59:20

PDGFRα/FLT3-ITD-IN-1 structure	Common Name	PDGFRα/FLT3-ITD-IN-1
	CAS Number	2761259-05-4	Molecular Weight	505.66
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₉N₉O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PDGFRα/FLT3-ITD-IN-1

PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-1

Description	PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₇H₃₉N₉O
Molecular Weight	505.66

PDGFRα/FLT3-ITD-IN-1

Use of PDGFRα/FLT3-ITD-IN-1

Names

PDGFRα/FLT3-ITD-IN-1 Biological Activity

Chemical & Physical Properties