PDGFRα/FLT3-ITD-IN-1

Modify Date: 2024-04-12 19:59:20

PDGFRα/FLT3-ITD-IN-1 Structure
PDGFRα/FLT3-ITD-IN-1 structure
Common Name PDGFRα/FLT3-ITD-IN-1
CAS Number 2761259-05-4 Molecular Weight 505.66
Density N/A Boiling Point N/A
Molecular Formula C27H39N9O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PDGFRα/FLT3-ITD-IN-1


PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

 Names

Name PDGFRα/FLT3-ITD-IN-1

 PDGFRα/FLT3-ITD-IN-1 Biological Activity

Description PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog
References

[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

 Chemical & Physical Properties

Molecular Formula C27H39N9O
Molecular Weight 505.66
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