PDGFRα/FLT3-ITD-IN-2

Modify Date: 2025-10-25 21:30:15

PDGFRα/FLT3-ITD-IN-2 structure	Common Name	PDGFRα/FLT3-ITD-IN-2
	CAS Number	2761259-09-8	Molecular Weight	519.68
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₄₁N₉O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PDGFRα/FLT3-ITD-IN-2

PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-2

Description	PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₈H₄₁N₉O
Molecular Weight	519.68
InChIKey	LEPCIRKHMJHAPC-UHFFFAOYSA-N
SMILES	NCCCCNC(=O)c1ccc(CNc2nc(NC3CCC(N)CC3)nc3c2ncn3C2CCCC2)cc1

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PDGFRα/FLT3-ITD-IN-2

Use of PDGFRα/FLT3-ITD-IN-2

Names

PDGFRα/FLT3-ITD-IN-2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.