NLRP3-IN-11

Modify Date: 2024-04-07 18:36:26

NLRP3-IN-11 Structure
NLRP3-IN-11 structure
Common Name NLRP3-IN-11
CAS Number 2769040-91-5 Molecular Weight 344.80
Density N/A Boiling Point N/A
Molecular Formula C17H17ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NLRP3-IN-11


NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].

 Names

Name NLRP3-IN-11

 NLRP3-IN-11 Biological Activity

Description NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].
Related Catalog
Target

NLRP3:<0.3 μM (IC50)

In Vitro NLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay[1]
References

[1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.

 Chemical & Physical Properties

Molecular Formula C17H17ClN4O2
Molecular Weight 344.80