ALK5-IN-9 structure
|
Common Name | ALK5-IN-9 | ||
---|---|---|---|---|
CAS Number | 2489611-06-3 | Molecular Weight | 572.62 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C29H35F3N6O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ALK5-IN-9ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1]. |
Name | ALK5-IN-9 |
---|
Description | ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1]. |
---|---|
Related Catalog | |
References |
Molecular Formula | C29H35F3N6O3 |
---|---|
Molecular Weight | 572.62 |