ALK5-IN-9
Modify Date: 2024-04-10 17:43:28
ALK5-IN-9 structure
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Common Name | ALK5-IN-9 | ||
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| CAS Number | 2489611-06-3 | Molecular Weight | 572.62 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H35F3N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ALK5-IN-9ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1]. |
| Name | ALK5-IN-9 |
|---|
| Description | ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C29H35F3N6O3 |
|---|---|
| Molecular Weight | 572.62 |