SIRT5 inhibitor 6

Modify Date: 2025-08-26 07:10:16

SIRT5 inhibitor 6 structure	Common Name	SIRT5 inhibitor 6
	CAS Number	2834736-82-0	Molecular Weight	460.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₈N₆O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SIRT5 inhibitor 6

SIRT5 Inhibitor 6 is a potent, substrate-competitive and selective SIRT5 inhibitor with an IC50 of 3.0 μM. SIRT5 Inhibitor6 has a therapeutic potential against septic AKI in vivo[1].

Name	SIRT5 inhibitor 6

Description	SIRT5 Inhibitor 6 is a potent, substrate-competitive and selective SIRT5 inhibitor with an IC50 of 3.0 μM. SIRT5 Inhibitor6 has a therapeutic potential against septic AKI in vivo[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Inflammation/Immunology
References	[1]. Luohe Mou, et al, Structure-Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney Injury. J Med Chem. 2023 Aug 24;66(16):11517-11535.

Molecular Formula	C₂₁H₂₈N₆O₄S
Molecular Weight	460.55
InChIKey	CEAPZJWXJWNRMC-UHFFFAOYSA-N
SMILES	CCOC(=O)c1cnc(NCc2ccccc2)nc1NCCCNC(=S)NCCC(=O)O

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