PROTAC GPX4 degrader-1
Modify Date: 2025-09-10 11:24:27
PROTAC GPX4 degrader-1 structure
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Common Name | PROTAC GPX4 degrader-1 | ||
|---|---|---|---|---|
| CAS Number | 2916433-81-1 | Molecular Weight | 993.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C50H57ClN10O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC GPX4 degrader-1PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells[1]. |
| Name | PROTAC GPX4 degrader-1 |
|---|
| Description | PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells[1]. |
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| Related Catalog | |
| In Vitro | PROTAC GPX4 degrader-1 (DC-2) has been found to induce GPX4 degradation and subsequent ferroptosis[1]. Western Blot Analysis[1]. Cell Line: HT1080 cells. Concentration: 0.003-1 μM. Incubation Time: 24 h. Result: Dose-dependently degraded GPX4 protein levels. |
| References |
| Molecular Formula | C50H57ClN10O10 |
|---|---|
| Molecular Weight | 993.50 |
| InChIKey | HMSNFNLFZRKDIO-UHFFFAOYSA-N |
| SMILES | Cc1onc(C(=O)N2CCN(C(c3ccc(Cl)cc3)c3ccc(OCC(=O)N4CCC(CN5CCN(CCCNc6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)cc3)CC2)c1[N+](=O)[O-] |