Bax BH3 peptide (55-74), wild type

Modify Date: 2025-08-25 14:33:37

Bax BH3 peptide (55-74), wild type Structure
Bax BH3 peptide (55-74), wild type structure
Common Name Bax BH3 peptide (55-74), wild type
CAS Number 299946-20-6 Molecular Weight 2267.60
Density N/A Boiling Point N/A
Molecular Formula C93H163N27O34S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bax BH3 peptide (55-74), wild type


Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models[1].

 Names

Name Bax BH3 peptide (55-74), wild type

 Bax BH3 peptide (55-74), wild type Biological Activity

Description Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models[1].
Related Catalog
In Vitro In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, Bax BH3 peptide (55-74), wild type can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death[1].
References

[1]. Peter E Czabotar, et al. Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis. J Biol Chem. 2011 Mar 4;286(9):7123-31.

 Chemical & Physical Properties

Molecular Formula C93H163N27O34S2
Molecular Weight 2267.60
InChIKey JEUJPRDOTFWCHJ-RRRSFJALSA-N
SMILES CCC(C)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CS)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(N)CO)C(C)O)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CCSC)C(=O)O
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