PD 118057
Modify Date: 2026-07-01 10:51:14
PD 118057 structure
|
Common Name | PD 118057 | ||
|---|---|---|---|---|
| CAS Number | 313674-97-4 | Molecular Weight | 386.27 | |
| Density | 1.353g/cm3 | Boiling Point | 527ºC at 760 mmHg | |
| Molecular Formula | C21H17Cl2NO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 272.52ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of PD 118057PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade[1]. |
| Name | 2-[4-[2-(3,4-dichlorophenyl)ethyl]anilino]benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade[1]. |
|---|---|
| Related Catalog | |
| Target |
Human ether-a-go-go-related gene channel[1] |
| References |
| Density | 1.353g/cm3 |
|---|---|
| Boiling Point | 527ºC at 760 mmHg |
| Molecular Formula | C21H17Cl2NO2 |
| Molecular Weight | 386.27 |
| Flash Point | 272.52ºC |
| Exact Mass | 385.06400 |
| PSA | 49.33000 |
| LogP | 6.29340 |
| Index of Refraction | 1.668 |
| InChIKey | ZCQOSCDABPVAFB-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccccc1Nc1ccc(CCc2ccc(Cl)c(Cl)c2)cc1 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H413 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | NONH for all modes of transport |
|
Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4513082
|
|
Name: Activation of human TREK-1 expressed in CHO cells at 10 uM in presence of ML335 by pa...
Source: ChEMBL
Target: Potassium channel subfamily K member 2
External Id: CHEMBL5125923
|
|
Name: Inhibition of amyloid beta (1 to 42) aggregation after 24 hrs by Thioflavin-T fluores...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2176106
|
|
Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
|
|
Name: Human Kv11.1 (Voltage-gated potassium channels)
Source: IUPHAR-DB
Target: Kv11.1 (Voltage-gated potassium channels) [Homo sapiens]
External Id: 572_Human
|
|
Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303805
|
|
Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
|
|
Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
|
|
Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
|
|
Name: Reduction in mean senile plaque area in Tg2576 mouse overexpressing human betaAPP695S...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL993093
|
Total 16, Current Page 1 of 2
1
2
| 2-[[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]amino]benzoic acid |