4-Acetoxyphenol

Modify Date: 2025-08-28 00:58:29

4-Acetoxyphenol Structure
4-Acetoxyphenol structure
Common Name 4-Acetoxyphenol
CAS Number 3233-32-7 Molecular Weight 152.14700
Density 1.212g/cm3 Boiling Point 269.3ºC at 760 mmHg
Molecular Formula C8H8O3 Melting Point N/A
MSDS N/A Flash Point 118.6ºC

 Use of 4-Acetoxyphenol


4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1].

 Names

Name 4-hydroxyphenyl acetate
Synonym More Synonyms

 4-Acetoxyphenol Biological Activity

Description 4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 4-Hydroxyphenyl acetate (5 μM; 24 h) protects retinal pigment epithelial (RPE) cells from oxidative stress-induced cell death[1]. 4-Hydroxyphenyl acetate (5 μM; 24 h; ARPE-19 cells) inhibits the increase of ROS in response to oxidative stress and up-regulated the expression of cytoprotective genes including NQO1 and HO-1 genes[1]. Cell Viability Assay[1] Cell Line: ARPE-19 cells Concentration: 5 μM Incubation Time: 24 hours Result: Protected up to 89%, 92%, and 90% of ARPE-19 cells exposed to 100, 200, and 300 μM tBHP, respectively.

 Chemical & Physical Properties

Density 1.212g/cm3
Boiling Point 269.3ºC at 760 mmHg
Molecular Formula C8H8O3
Molecular Weight 152.14700
Flash Point 118.6ºC
Exact Mass 152.04700
PSA 46.53000
LogP 1.31750
Index of Refraction 1.541
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synonyms

p-acetoxyphenol
p-hydroxyphenyl acetate
4-Acetoxyphenol
1,4-Benzenediol,monoacetate
(4-hydroxyphenyl) acetate
hydroquinone acetate
4-hydroxyphenylacetat
4-Hydroxyphenyl acetate
hydroquinone monoacetate
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