4-Acetoxyphenol
Modify Date: 2024-01-05 17:30:14
4-Acetoxyphenol structure
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Common Name | 4-Acetoxyphenol | ||
|---|---|---|---|---|
| CAS Number | 3233-32-7 | Molecular Weight | 152.14700 | |
| Density | 1.212g/cm3 | Boiling Point | 269.3ºC at 760 mmHg | |
| Molecular Formula | C8H8O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 118.6ºC | |
Use of 4-Acetoxyphenol4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1]. |
| Name | 4-hydroxyphenyl acetate |
|---|---|
| Synonym | More Synonyms |
| Description | 4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | 4-Hydroxyphenyl acetate (5 μM; 24 h) protects retinal pigment epithelial (RPE) cells from oxidative stress-induced cell death[1]. 4-Hydroxyphenyl acetate (5 μM; 24 h; ARPE-19 cells) inhibits the increase of ROS in response to oxidative stress and up-regulated the expression of cytoprotective genes including NQO1 and HO-1 genes[1]. Cell Viability Assay[1] Cell Line: ARPE-19 cells Concentration: 5 μM Incubation Time: 24 hours Result: Protected up to 89%, 92%, and 90% of ARPE-19 cells exposed to 100, 200, and 300 μM tBHP, respectively. |
| Density | 1.212g/cm3 |
|---|---|
| Boiling Point | 269.3ºC at 760 mmHg |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.14700 |
| Flash Point | 118.6ºC |
| Exact Mass | 152.04700 |
| PSA | 46.53000 |
| LogP | 1.31750 |
| Index of Refraction | 1.541 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi |
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| Precursor 9 | |
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| DownStream 7 | |
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CAS#:89210-89-9| p-acetoxyphenol |
| p-hydroxyphenyl acetate |
| 4-Acetoxyphenol |
| 1,4-Benzenediol,monoacetate |
| (4-hydroxyphenyl) acetate |
| hydroquinone acetate |
| 4-hydroxyphenylacetat |
| 4-Hydroxyphenyl acetate |
| hydroquinone monoacetate |