3,5-Dichloro-4-hydroxybenzoic acid

Modify Date: 2025-08-26 21:45:31

3,5-Dichloro-4-hydroxybenzoic acid Structure
3,5-Dichloro-4-hydroxybenzoic acid structure
Common Name 3,5-Dichloro-4-hydroxybenzoic acid
CAS Number 3336-41-2 Molecular Weight 207.011
Density 1.7±0.1 g/cm3 Boiling Point 328.2±42.0 °C at 760 mmHg
Molecular Formula C7H4Cl2O3 Melting Point 264-266 °C(lit.)
MSDS Chinese USA Flash Point 152.3±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,5-Dichloro-4-hydroxybenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 328.2±42.0 °C at 760 mmHg
Melting Point 264-266 °C(lit.)
Molecular Formula C7H4Cl2O3
Molecular Weight 207.011
Flash Point 152.3±27.9 °C
Exact Mass 205.953751
PSA 57.53000
LogP 3.37
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.641
InChIKey AULKDLUOQCUNOK-UHFFFAOYSA-N
SMILES O=C(O)c1cc(Cl)c(O)c(Cl)c1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG7502000
CHEMICAL NAME :
Benzoic acid, 3,5-dichloro-4-hydroxy-
CAS REGISTRY NUMBER :
3336-41-2
BEILSTEIN REFERENCE NO. :
2616297
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H4-Cl2-O3
MOLECULAR WEIGHT :
207.01
WISWESSER LINE NOTATION :
QVR DQ CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
650 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,213,1960

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG7502000
HS Code 2918290000

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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 3,5-Dichloro-4-hydroxybenzoic acidBioassay

View more

Name: qHTS assay for inhibitors of human lactate dehydrogenase
Source: NCGC
Target: N/A
External Id: LDHA
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-FF
Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-Ren
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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 Synonyms

4-hydroxy-3,5-dichloro-benzoic acid
BENZOIC ACID,3,5-DICHLORO-4-HYDROXY
acide dichloro-3,5 hydroxy-4 benzoique
DiClHBz
3,5-Dichloro-4-hydroxybenzoic acid
EINECS 222-071-9
3,5-dichloro-4-hydroxy-benzoic acid
3,5-Dichloro-4-hydroxybenzoicAcid
3,5-Dichlor-4-hydroxy-benzoesaeure
MFCD00002550
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