PNU-248686A

Modify Date: 2023-05-31 20:01:26

Use of PNU-248686A

PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.

Name	PNU-248686A
Synonym	More Synonyms

Description	PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.
Related Catalog	Research Areas >> Cancer
Target	MMP[1]
In Vitro	PNU-248686A is an orally active matrix metalloproteinase (MMP) inhibitor developed for the treatment of solid tumors over-expressing MMPs[1].
References	[1]. Frigerio E, et al. Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J Chromatogr A. 2003 Feb 14;987(1-2):249-56.

Sodium (2R)-3-[(4'-chloro-4-biphenylyl)sulfonyl]-2-hydroxy-2-[(phenylsulfanyl)methyl]propanoate

Propanoic acid, 3-[(4'-chloro[1,1'-biphenyl]-4-yl)sulfonyl]-2-hydroxy-2-[(phenylthio)methyl]-, sodium salt, (2R)- (1:1)