Echinatin

Modify Date: 2024-01-02 08:18:14

Echinatin Structure
Echinatin structure
Common Name Echinatin
CAS Number 34221-41-5 Molecular Weight 270.280
Density 1.3±0.1 g/cm3 Boiling Point 509.8±50.0 °C at 760 mmHg
Molecular Formula C16H14O4 Melting Point 210ºC (dec.)
MSDS N/A Flash Point 193.3±23.6 °C

 Use of Echinatin


Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2].

 Names

Name (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Synonym More Synonyms

 Echinatin Biological Activity

Description Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2].
Related Catalog
References

[1]. Liang M, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A. Molecules. 2018 Dec 20;24(1).

[2]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 509.8±50.0 °C at 760 mmHg
Melting Point 210ºC (dec.)
Molecular Formula C16H14O4
Molecular Weight 270.280
Flash Point 193.3±23.6 °C
Exact Mass 270.089203
PSA 66.76000
LogP 3.23
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.658
Storage condition 2-8°C

 Safety Information

HS Code 2914509090

 Synthetic Route

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Echinatin Structure

Echinatin

CAS#:34221-41-5

Literature: Achenbach, Hans; Stoecker, Markus; Constenla, Manuel A. Phytochemistry (Elsevier), 1988 , vol. 27, # 6 p. 1835 - 1842

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Echinatin Structure

Echinatin

CAS#:34221-41-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 11 p. 3320 - 3324

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Echinatin Structure

Echinatin

CAS#:34221-41-5

Literature: Phytochemistry (Elsevier), , vol. 19, p. 2179 - 2184

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

Echinatin
Retrochalcone
(2E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one
Echinantin
2-Propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-
2-methoxy-4,4'-dihydroxychalcone
(2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
loureirin C
(E)-4,4'-Dihydroxy-2-methoxychalcone
4',4-dihydroxy-2-methoxychalcone
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  • BioBioPha
  • China
  • Product Name: Echinatin
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng




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