DL-Dithiothreitol

Modify Date: 2024-01-02 09:04:15

DL-Dithiothreitol Structure
DL-Dithiothreitol structure
Common Name DL-Dithiothreitol
CAS Number 3483-12-3 Molecular Weight 154.251
Density 1.3±0.1 g/cm3 Boiling Point 364.5±42.0 °C at 760 mmHg
Molecular Formula C4H10O2S2 Melting Point 38-43ºC
MSDS Chinese USA Flash Point 174.2±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of DL-Dithiothreitol


DTT is a small-molecule redox reagent.

 Names

Name 1,4-dithiothreitol
Synonym More Synonyms

 DL-Dithiothreitol Biological Activity

Description DTT is a small-molecule redox reagent.
Related Catalog
References

[1]. Dithiothreitol, From Wikipedia

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 364.5±42.0 °C at 760 mmHg
Melting Point 38-43ºC
Molecular Formula C4H10O2S2
Molecular Weight 154.251
Flash Point 174.2±27.9 °C
Exact Mass 154.012222
PSA 118.06000
LogP 0.07
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.579
Storage condition 2-8°C
Stability Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents. Keep frozen at -20 to -10 C.
Water Solubility H2O: 50 mg/mL, clear, colorless | freely soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK1610000
CHEMICAL NAME :
2,3-Butanediol, 1,4-dimercapto-, D-threo-
CAS REGISTRY NUMBER :
3483-12-3
LAST UPDATED :
199707
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H10-O2-S2
MOLECULAR WEIGHT :
154.26
WISWESSER LINE NOTATION :
SH1YQYQ1SH -D,THREO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
154 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
108 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 1,576,1949 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7467 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1196 (estimated) No. of Female Employees: 906 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S37/39
RIDADR UN 3335
WGK Germany 3
RTECS EK1610000
HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

DITHIOERYTHRITOL
DL-1,4-Dithiothreitol
DTT
1,4-Dithiothreitol
1,4-Bissulfanylbutane-2,3-diol
DL-1,4-Dimercapto-2,3-dihydroxybutane
2,3-Butanediol, 1,4-dimercapto-, (2S,3S)-
THREO-2,3-DIHYDROXY-1,4-DITHIOLBUTANE
1,4-Disulfanyl-2,3-butanediol
Threitol, 1,4-dithio-
(R*,R*)-1,4-DIMERCAPTO-2,3-BUTANEDIOL
EINECS 222-468-7
(2S,3S)-1,4-Disulfanyl-2,3-butanediol
Cleland's Reagent
DL-Dithiothreitol
(2R*,3S*)-1,4-dimercaptobutane-2,3-diol
(2S,3S)-1,4-Disulfanylbutane-2,3-diol
threo-2,3-Dihydroxy-1,4-butanedithiol
dithiothreitol
(2R*,3S*)-1,4-dimercapto-2,3-butanediol
Sputolysin
threo-1,4-Dimercapto-2,3-butanediol
1,4-Disulfanylbutane-2,3-diol
2,3-Butanediol, 1,4-dimercapto-
MFCD00004877
(±)-1,4-Dimercapto-2,3-butanediol
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