HO-PEG17-OH

Modify Date: 2024-01-14 09:42:29

HO-PEG17-OH Structure
HO-PEG17-OH structure
Common Name HO-PEG17-OH
CAS Number 351342-04-6 Molecular Weight 766.91
Density N/A Boiling Point N/A
Molecular Formula C34H70O18 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HO-PEG17-OH


HO-PEG17-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG18
Synonym More Synonyms

 HO-PEG17-OH Biological Activity

Description HO-PEG17-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H70O18
Molecular Weight 766.91

 Synonyms

MFCD28976675