2-Guanidinoacetic acid

Modify Date: 2026-07-03 14:19:26

2-Guanidinoacetic acid Structure
2-Guanidinoacetic acid structure
 Common Name 2-Guanidinoacetic acid
CAS Number 352-97-6 Molecular Weight 117.107
Density 1.6±0.1 g/cm3 Boiling Point 294.2±42.0 °C at 760 mmHg
Molecular Formula C3H7N3O2 Melting Point 300 °C(lit.)
MSDS Chinese USA Flash Point 131.7±27.9 °C

 Use of 2-Guanidinoacetic acid


2-Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name guanidinoacetic acid
Synonym More Synonyms

 2-Guanidinoacetic acid Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 2-Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Dilger RN, et al. Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. Poult Sci. 2013 Jan;92(1):171-7.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.6±0.1 g/cm3
Boiling Point 294.2±42.0 °C at 760 mmHg
Melting Point 300 °C(lit.)
Molecular Formula C3H7N3O2
Molecular Weight 117.107
Flash Point 131.7±27.9 °C
Exact Mass 117.053825
PSA 99.20000
LogP -1.85
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.596
InChIKey BPMFZUMJYQTVII-UHFFFAOYSA-N
SMILES NC(N)=NCC(=O)O
Water Solubility 6 M NaOH : 50 mg/mL, clear, colorless

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS MB7700000
HS Code 29252000

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles52

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

High-throughput tandem mass spectrometry multiplex analysis for newborn urinary screening of creatine synthesis and transport disorders, Triple H syndrome and OTC deficiency.

Clin. Chim. Acta 436 , 249-55, (2014)

Creatine synthesis and transport disorders, Triple H syndrome and ornithine transcarbamylase deficiency are treatable inborn errors of metabolism. Early screening of patients was found to be beneficia...

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.

Kidney Int. 59(6) , 2267-72, (2001)

Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl tran...

 2-Guanidinoacetic acidBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: In vivo blood glucose was determined in obese, hyperglycemic, hyperinsulinemic, insul...
Source: ChEMBL
Target: N/A
External Id: CHEMBL702244
Name: Percentage inhibition against tryptase at 10 uM
Source: ChEMBL
Target: Tryptase alpha/beta-1
External Id: CHEMBL832048
Name: In vivo blood glucose was determined in obese, hyperglycemic, hyperinsulinemic, insul...
Source: ChEMBL
Target: N/A
External Id: CHEMBL702243
Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
Name: Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 ...
Source: ChEMBL
Target: Proton-coupled amino acid transporter 1
External Id: CHEMBL1919336
Name: MELAS cybrid survival enhancement under low glucose conditions
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1419
Name: Inhibition of [3H]GABA binding to Gamma-aminobutyric acid A (GABA-A) receptor of rat ...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-3
External Id: CHEMBL686133
Total 8, Current Page 1 of 1
1

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Guanidinoacetic acid
Acide carbamimidamidoacétique
Guanyl glycine
Guanidineacetic acid
[(aminoiminomethyl)amino]-Acetic acid
(carboxymethyl)-Guanidine
Betasyamine
α-Guanidinoacetic acid
N-Amidinoglycine
Guanidylacetic acid
amidinoglycine
N-(Aminoiminomethyl)glycine
N-amidino-Glycine
2-(diaminomethylideneamino)acetic acid
2-[[Amino(imino)methyl]amino]acetic acid
Glycocyamine
N-Carbamimidoylglycine
a-Guanidinoacetic acid
Carbamimidamidoacetic acid
Guanidoacetic acid
EINECS 206-529-5
N-Guanylglycine
{[Ammonio(imino)methyl]amino}acetate
Guanidinooacetic Acid
2-Guanidinoacetic acid
Betacyamine
MFCD00004278

 2-Guanidinoacetic acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of guanidinoacetic acid?
A: Boiling point of guanidinoacetic acid is 294.2±42.0 °C at 760 mmHg.
Q: What is the melting point of guanidinoacetic acid?
A: Melting point of guanidinoacetic acid is 300 °C(lit.).
Q: What is the molecular formula of guanidinoacetic acid?
A: Molecular formula of guanidinoacetic acid is C3H7N3O2.
Q: What is the English name of guanidinoacetic acid?
A: The English name of guanidinoacetic acid is guanidinoacetic acid.
Q: What is the InChIKey of guanidinoacetic acid?
A: InChIKey of guanidinoacetic acid is BPMFZUMJYQTVII-UHFFFAOYSA-N.
Q: What is the LogP of guanidinoacetic acid?
A: LogP of guanidinoacetic acid is -1.85.
Q: What is the CAS number of guanidinoacetic acid?
A: CAS number of guanidinoacetic acid is 352-97-6.
Q: What are the uses of guanidinoacetic acid?
A: Main uses of guanidinoacetic acid: 2-Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.
Q: What are the upstream materials of guanidinoacetic acid?
A: Related upstream materials(CAS) of guanidinoacetic acid: 56-40-6;1184-90-3;74-79-3;1758-73-2;113-00-8;79-11-8;77287-34-4;543-83-9;420-04-2.
Q: What is the safety information for guanidinoacetic acid?
A: Safety information for guanidinoacetic acid: S26-S36.

 2-Guanidinoacetic acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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