(Ala1)-PAR-4 (1-6) amide (mouse) trifluoroacetate salt
Modify Date: 2024-01-02 08:28:39
(Ala1)-PAR-4 (1-6) amide (mouse) trifluoroacetate salt structure
|
Common Name | (Ala1)-PAR-4 (1-6) amide (mouse) trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 352017-71-1 | Molecular Weight | 680.79400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H48N8O7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of (Ala1)-PAR-4 (1-6) amide (mouse) trifluoroacetate saltPAR-4 Agonist Peptide, amide is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. |
| Name | ay-nh2 |
|---|---|
| Synonym | More Synonyms |
| Description | PAR-4 Agonist Peptide, amide is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. |
|---|---|
| Related Catalog | |
| Target |
PAR-4[1] |
| In Vivo | Compared with their BALB/cBy controls, SCID mice have a significantly greater abdominal response to colorectal distension (CRD) at the distension levels of 0.04 to 0.1 mL increasing the intensity of EMG response by 384% to 132%, respectively (P<0.01; P<0.01; P<0.01; P<0.001). PAR-4 activation effectively reverses this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05) [1]. |
| Animal Admin | Mice[1] SCID mice Male SCID mice and their BALB/cBy controls are operated as C57BL/6J mice, and on the 4th postoperative day mice receive intracolonically (IC) infusion of 100 μg PAR-4-AP or vehicle. Visceral pain measurements started 1 h following the end of infusion[1]. |
| References |
| Molecular Formula | C34H48N8O7 |
|---|---|
| Molecular Weight | 680.79400 |
| Exact Mass | 680.36500 |
| PSA | 252.07000 |
| LogP | 2.30290 |
| Storage condition | 2-8℃ |
| Safety Phrases | S22-S24/25 |
|---|
| Proteinase activated receptor 4 amide,mouse |
| PAR-4 AGONIST AMIDE |
| ALA-TYR-PRO-GLY-LYS-PHE-NH2 |
| AYPGKFAMIDE |
| PROTEASE-ACTIVATED RECEPTOR-4 AGONIST AMIDE |
| H-ALA-TYR-PRO-GLY-LYS-PHE-NH2 |
| AYPGKF-NH2 |
| (Ala1)-PAR-4 (1-6) amide (mouse) |
| PAR-4 Agonist Peptide, amide |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: AYPGKF-NH2
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- DC Chemicals Limited
- China
- Product Name: AY-NH2
- Price: $3500.0/1g $950.0/100mg $1800.0/250mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: AY-NH2
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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Price: ￥1100/1 mg
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