Amino-PEG12-amine

Modify Date: 2024-01-09 01:34:09

Amino-PEG12-amine Structure
Amino-PEG12-amine structure
Common Name Amino-PEG12-amine
CAS Number 361543-12-6 Molecular Weight 588.73
Density N/A Boiling Point N/A
Molecular Formula C26H56N2O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG12-amine


Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG12-amine

 Amino-PEG12-amine Biological Activity

Description Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C26H56N2O12
Molecular Weight 588.73
Storage condition 2-8°C