EA4
Modify Date: 2024-01-12 11:35:50
EA4 structure
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Common Name | EA4 | ||
|---|---|---|---|---|
| CAS Number | 389614-94-2 | Molecular Weight | 340.803 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 508.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H17ClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 261.2±30.1 °C | |
Use of EA4EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1]. |
| Name | 7-chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione |
|---|---|
| Synonym | More Synonyms |
| Description | EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1]. |
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| Related Catalog | |
| Target |
Ki: 130 μM (rPLA2)[1] |
| In Vitro | EA4（9 μM，24 μM）抑制 rPLA2 和 cPLA2[1]。 EA4 可抑制 rPLA2，Ki 值为 130 μM[1]。 EA4 (50 μM) 以时间依赖性方式显著抑制 A23187 诱导的人和牛红细胞释放 AA[1]。 |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 508.3±50.0 °C at 760 mmHg |
| Molecular Formula | C19H17ClN2O2 |
| Molecular Weight | 340.803 |
| Flash Point | 261.2±30.1 °C |
| Exact Mass | 340.097870 |
| PSA | 50.27000 |
| LogP | 4.42 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.634 |
| 7-Chloro-6-[4-(diethylamino)phenyl]-5,8-quinolinedione |
| 5,8-Quinolinedione, 7-chloro-6-[4-(diethylamino)phenyl]- |
| ea4 |