GS 39783

Modify Date: 2025-08-28 21:35:08

GS 39783 Structure
GS 39783 structure
Common Name GS 39783
CAS Number 39069-52-8 Molecular Weight 337.44000
Density 1.3g/cm3 Boiling Point 561.9ºC at 760 mmHg
Molecular Formula C15H23N5O2S Melting Point N/A
MSDS Chinese USA Flash Point 293.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of GS 39783


GS39783 is a positive allosteric modulator (PAM) of GABABR. Positive modulation of the GABABR can be used for the research of Nicotine addiction[1].

 Names

Name 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine
Synonym More Synonyms

 GS 39783 Biological Activity

Description GS39783 is a positive allosteric modulator (PAM) of GABABR. Positive modulation of the GABABR can be used for the research of Nicotine addiction[1].
Related Catalog
References

[1]. Emmanuel Sturchler, et al. GABA B receptor allosteric modulators exhibit pathway-dependent and species-selective activity. Pharmacol Res Perspect. 2017 Mar 24;5(2):e00288.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 561.9ºC at 760 mmHg
Molecular Formula C15H23N5O2S
Molecular Weight 337.44000
Flash Point 293.7ºC
Exact Mass 337.15700
PSA 120.96000
LogP 4.48490
Index of Refraction 1.614
InChIKey GSGVDKOCBKBMGG-UHFFFAOYSA-N
SMILES CSc1nc(NC2CCCC2)c([N+](=O)[O-])c(NC2CCCC2)n1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P301 + P312 + P330-P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

Tocris-2001
N,N'-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine
N4,N6-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine
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