4-Trifluoromethylanthranilic acid

Modify Date: 2024-01-09 09:16:11

4-Trifluoromethylanthranilic acid Structure
4-Trifluoromethylanthranilic acid structure
Common Name 4-Trifluoromethylanthranilic acid
CAS Number 402-13-1 Molecular Weight 205.134
Density 1.5±0.1 g/cm3 Boiling Point 296.0±40.0 °C at 760 mmHg
Molecular Formula C8H6F3NO2 Melting Point 175-176°C
MSDS USA Flash Point 132.8±27.3 °C

 Names

Name 2-Amino-4-(trifluoromethyl)benzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 296.0±40.0 °C at 760 mmHg
Melting Point 175-176°C
Molecular Formula C8H6F3NO2
Molecular Weight 205.134
Flash Point 132.8±27.3 °C
Exact Mass 205.035065
PSA 63.32000
LogP 3.30
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.528

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 36
Safety Phrases 26
HS Code 2922499990

 Synthetic Route

~99%

4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2006/108591 A1, 2006 ; Location in patent: Page/Page column 10; 66 ; WO 2006/108591 A1

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4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: Sandoz, Inc. Patent: US4307113 A1, 1981 ;

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4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: Suez, Gal; Bloch, Victoria; Nisnevich, Gennady; Gandelman, Mark European Journal of Organic Chemistry, 2012 , # 11 p. 2118 - 2122

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4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: Saucy,G.; Sternbach,L.H. Helvetica Chimica Acta, 1962 , vol. 45, p. 2226 - 2241

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4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: Rowley, Michael; Leeson, Paul D.; Stevenson, Graeme I.; Moseley, Angela M.; Stansfield, Ian; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 22 p. 3386 - 3396

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4-Trifluoromethylanthranilic acid Structure

4-Trifluorometh...

CAS#:402-13-1

Literature: Giencke, Astrid; Lackner, Helmut Liebigs Annalen der Chemie, 1990 , # 6 p. 569 - 579

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

2-Amino-4-(trifluoromethyl)benzoic acid
4-Trifluoromethylanthranilic acid
Benzoic acid, 2-amino-4-(trifluoromethyl)-
4-(Trifluoromethyl)anthranilic Acid
EINECS 206-937-3
MFCD00519334