Folic Acid

Modify Date: 2024-01-01 20:16:34

Folic Acid structure	Common Name	Folic Acid
	CAS Number	59-30-3	Molecular Weight	441.397
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₉N₇O₆	Melting Point	250 °C
	MSDS	Chinese USA	Flash Point	N/A

Use of Folic Acid

Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

Name	folic acid
Synonym	More Synonyms

Description	Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Natural Products >> Others Research Areas >> Others

Density	1.6±0.1 g/cm3
Melting Point	250 °C
Molecular Formula	C₁₉H₁₉N₇O₆
Molecular Weight	441.397
Exact Mass	441.139679
PSA	213.28000
LogP	-2.48
Index of Refraction	1.755
Storage condition	2~8°C
Water Solubility	1.6 mg/L (25 ºC)

Folic Acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LP5425000

CHEMICAL NAME :: Folic acid

CAS REGISTRY NUMBER :: 59-30-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C19-H19-N7-O6

MOLECULAR WEIGHT :: 441.45

WISWESSER LINE NOTATION :: T66 BN DN GN JNJ CZ EQ H1MR DVMYVQ2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Behavioral - coma

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - changes in spleen

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 282 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 410 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 150 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Unscheduled DNA synthesis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,136,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1051 No. of Facilities: 220 (estimated) No. of Industries: 4 No. of Occupations: 14 No. of Employees: 11106 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1051 No. of Facilities: 2823 (estimated) No. of Industries: 11 No. of Occupations: 40 No. of Employees: 60281 (estimated) No. of Female Employees: 29903 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R33;R62;R68
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	LP5425000
HS Code	2936290090

Precursor 5
CAS#:58-05-9 Folinic acid CAS#:10016-20-3 α-Cyclodextrin CAS#:65165-92-6 pteroylmonoglut... CAS#:497-15-4 Glucic acid
CAS#:4271-30-1 N-(4-aminobenzo...
DownStream 9
CAS#:31690-09-2 Levomefolic acid CAS#:4230-33-5 N-(4-Aminobenzo... CAS#:712-30-1 2-Amino-4-hydro... CAS#:54-62-6 Aminopterin
CAS#:37793-53-6 N10-(Trifluoroa... CAS#:4271-30-1 N-(4-aminobenzo... CAS#:948-60-7 Pterin-6-carbox... CAS#:150-13-0 4-Aminobenzoic acid
CAS#:4033-27-6 Dihydrofolic acid

HS Code	2936290090

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glutamic acid, N-[4-[[(2-amino-4,8-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-

VM/PGA

Folbal

folic

FOLSAN

Folic acid

Folate

N-[p-[[(2-Amino-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]glutamic Acid

EINECS 200-419-0

Folan

N-(p-[(2-Amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl)methylamino]benzoyl)glutamic Acid

pteroic acid-glutamate

Pteroyglutamic acid

Folsav

4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)-

PGA

MFCD00079305

PTEGLU

N-(4-{[(2-Amino-4-oxo-4,8-dihydropteridin-6-yl)methyl]amino}benzoyl)glutamic acid

2-[(4-{[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino}benzoyl)amino]pentanedioic acid

N-(4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoyl)glutamic acid

Aspol

N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)glutamic acid

Glutamic acid, N-[4-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-

N-(4-{[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino}benzoyl)glutamic acid

Folicacidhydrate

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Folic Acid
Price: ￥158.0/100mg ￥118.0/25g ￥218.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Folic acid
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Folic acid
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: folic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: $79/10mM*1mLinDMSO

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Folic Acid

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