DICHLOROACETIC ANHYDRIDE

Modify Date: 2024-01-03 19:14:25

DICHLOROACETIC ANHYDRIDE Structure
DICHLOROACETIC ANHYDRIDE structure
Common Name DICHLOROACETIC ANHYDRIDE
CAS Number 4124-30-5 Molecular Weight 239.86900
Density 1.695g/cm3 Boiling Point 215ºC at 760mmHg
Molecular Formula C4H2Cl4O3 Melting Point -30ºC
MSDS Chinese USA Flash Point 90.6ºC
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name dichloroacetic anhydride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.695g/cm3
Boiling Point 215ºC at 760mmHg
Melting Point -30ºC
Molecular Formula C4H2Cl4O3
Molecular Weight 239.86900
Flash Point 90.6ºC
Exact Mass 237.87600
PSA 43.37000
LogP 1.66360
Appearance of Characters Liquid After Melting | Clear colorless
Index of Refraction n20/D 1.483(lit.)
Storage condition Store below +30°C.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AG6300000
CHEMICAL NAME :
Acetic acid, dichloro-, anhydride
CAS REGISTRY NUMBER :
4124-30-5
BEILSTEIN REFERENCE NO. :
0512173
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H2-Cl4-O3
MOLECULAR WEIGHT :
239.86
WISWESSER LINE NOTATION :
GYGVOVYGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,574,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
470 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H311-H314-H332
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C
Risk Phrases R21;R34
Safety Phrases S26;S27;S28;S45;S36/S37/S39
RIDADR UN 2923 8/PG 3
WGK Germany 3
RTECS AG6300000
Packaging Group II
HS Code 2915900090

 Synthetic Route

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: Martin,D. Chemische Berichte, 1965 , vol. 98, p. 3286 - 3296

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: Anthoine Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, 1883 , p. 1032

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: Krieble; Smellie Patent: US2390106 , 1944 ;

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: I.G.Farbenind. Patent: FR703816 ; Full Text Show Details I.G.Farbenind. Patent: DE542421 , 1929 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 18, p. 284 Full Text Show Details I.G.Farbenind. Patent: US1967668 , 1930 ;

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: Baroni Gazzetta Chimica Italiana, 1933 , vol. 63, p. 23,33

~%

DICHLOROACETIC ANHYDRIDE Structure

DICHLOROACETIC ...

CAS#:4124-30-5

Literature: Baroni Gazzetta Chimica Italiana, 1933 , vol. 63, p. 23,33

~%

Detail
Literature: Krieble; Smellie Patent: US2390106 , 1944 ;

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride.

Toxicol. Appl. Pharmacol. 216(2) , 248-55, (2006)

Dichloroacetyl chloride (DCAC) is formed from trichloroethene (TCE), which is implicated in inducing/accelerating autoimmune response. Due to its potent acylating activity, DCAC may convert proteins t...

Selective enzymatic acylation of 10-deacetylbaccatin III. Lee D, et al.

Tetrahedron Lett. 39(49) , 9039-42, (1998)

A new soluble and hydrolytically cleavable intermediate in cellulose functionalization: cellulose dichloroacetate (CDCA). Liebert T and Klemm D.

Acta Polym. 49(2-3) , 124-28, (1998)

 Synonyms

(2,2-dichloroacetyl) 2,2-dichloroacetate
EINECS 223-924-8
MFCD00000842
Dichloroacetic anhydride