Procyanidin A2

Modify Date: 2025-08-24 00:26:52

Procyanidin A2 Structure
Procyanidin A2 structure
Common Name Procyanidin A2
CAS Number 41743-41-3 Molecular Weight 576.50
Density 1.766g/cm3 Boiling Point 946ºC at 760 mmHg
Molecular Formula C30H24O12 Melting Point N/A
MSDS USA Flash Point 525.9ºC

 Use of Procyanidin A2


Procyanidin A2 is a flavonoid found in cranberries and lingonberries, with anti-cancer, antioxidant, antimicrobial and anti-inflammation activity[1][2].

 Names

Name proanthocyanidin A2
Synonym More Synonyms

 Procyanidin A2 Biological Activity

Description Procyanidin A2 is a flavonoid found in cranberries and lingonberries, with anti-cancer, antioxidant, antimicrobial and anti-inflammation activity[1][2].
Related Catalog
Target

Bacterial[1]

In Vitro Procyanidin A2 shows DPPH radical scavenging activity, with an IC50 of 5.08 ± 0.37 μM[1].
References

[1]. LingrongWen, et al. Identification of flavonoids in litchi (Litchi chinensis Sonn.) leaf and evaluation of anticancer activities. Journal of Functional Foods. January 2014, 6, P: 555-563.

[2]. Coleman SL, et al. Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells. Int J Mol Sci. 2016 Nov 12;17(11).

 Chemical & Physical Properties

Density 1.766g/cm3
Boiling Point 946ºC at 760 mmHg
Molecular Formula C30H24O12
Molecular Weight 576.50
Flash Point 525.9ºC
Exact Mass 576.12700
PSA 209.76000
LogP 2.79350
Index of Refraction 1.829
InChIKey NSEWTSAADLNHNH-LSBOWGMISA-N
SMILES Oc1cc(O)c2c(c1)OC1(c3ccc(O)c(O)c3)Oc3cc(O)c4c(c3C2C1O)OC(c1ccc(O)c(O)c1)C(O)C4
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synthetic Route

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Nonaka, Gen-ichiro; Morimoto, Satoshi; Nishioka, Itsuo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2139 - 2145

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Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Balde, A. M.; Pieters, L. A.; Wray, V.; Kolodziej, H.; Berghe, D. A. Vanden; et al. Phytochemistry (Elsevier), 1991 , vol. 30, # 12 p. 4129 - 4136

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Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Balde, A. M.; Pieters, L. A.; Wray, V.; Kolodziej, H.; Berghe, D. A. Vanden; et al. Phytochemistry (Elsevier), 1991 , vol. 30, # 12 p. 4129 - 4136

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Kondo, Kazunari; Kurihara, Masaaki; Fukuhara, Kiyoshi; Tanaka, Takashi; Suzuki, Takashi; Miyata, Naoki; Toyoda, Masatake Tetrahedron Letters, 2000 , vol. 41, # 4 p. 485 - 488

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Nonaka, Gen-ichiro; Morimoto, Satoshi; Nishioka, Itsuo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2139 - 2145

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Nonaka, Gen-ichiro; Morimoto, Satoshi; Nishioka, Itsuo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2139 - 2145

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Morimoto, Satoshi; Nonaka, Gen-ichiro; Nishioka, Itsuo Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 12 p. 4717 - 4729

~%

Procyanidin A2 Structure

Procyanidin A2

CAS#:41743-41-3

Literature: Morimoto, Satoshi; Nonaka, Gen-ichiro; Nishioka, Itsuo Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 12 p. 4717 - 4729

 Procyanidin A2Bioassay

View more

Name: Inhibition against HIV replication in cell culture at 20 ug/mL
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL684469
Name: Inhibition of HIV1 protease
Source: ChEMBL
Target: Protease
External Id: CHEMBL971950
Name: Cytotoxicity against human PRMI7951 cells by tetrazolium salt-based colorimetric assa...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL941398
Name: Inhibition of PHA-stimulated human PBMC proliferation assessed as [3H]thymidine uptak...
Source: ChEMBL
Target: PBMC
External Id: CHEMBL1015621
Name: Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay
Source: ChEMBL
Target: A549
External Id: CHEMBL941400
Name: Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay
Source: ChEMBL
Target: KB
External Id: CHEMBL941399
Name: Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as change in...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL1954985
Name: Antibacterial activity against Staphylococcus epidermidis ATCC 35984 assessed as inhi...
Source: ChEMBL
Target: Staphylococcus epidermidis
External Id: CHEMBL1954984
Name: Inhibition of HIV1 protease at 100 ug/ml
Source: ChEMBL
Target: Protease
External Id: CHEMBL971951
Name: Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as change in...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL1954987
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 Synonyms

Procyanidin A2
7,4beta-&Procyanidol A2
8)-epicatechin
(2r,3r,8s,14r,15r)-2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-2h,14h-8,14-methanochromeno[7,8-d][1,3]benzodioxocine-3,5,11,13,15-pentol
Proanthocyanidin A-2
Proanthocyanidin A2
Epicatechin-(2beta-&Procyanidin dimer A2
Dimeric catechin
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