pht-ala-oh

Modify Date: 2026-07-10 12:17:38

pht-ala-oh Structure
pht-ala-oh structure
Common Name pht-ala-oh
CAS Number 4192-28-3 Molecular Weight 219.193
Density 1.5±0.1 g/cm3 Boiling Point 407.9±28.0 °C at 760 mmHg
Molecular Formula C11H9NO4 Melting Point 139 - 141ºC
MSDS USA Flash Point 200.5±24.0 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.5±0.1 g/cm3
Boiling Point 407.9±28.0 °C at 760 mmHg
Melting Point 139 - 141ºC
Molecular Formula C11H9NO4
Molecular Weight 219.193
Flash Point 200.5±24.0 °C
Exact Mass 219.053162
PSA 74.68000
LogP 1.54
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.629
InChIKey OZWUITKBAWTEAQ-LURJTMIESA-N
SMILES CC(C(=O)O)N1C(=O)c2ccccc2C1=O
Storage condition Store at 0°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Pht-Ala-OH
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Pht-Ala-OH
CAS number:4192-28-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C11H9NO4
Molecular weight: 219.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes T
Risk Phrases 25
Safety Phrases 45

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~97%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678

~85%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Zhang, Qi; Chen, Kai; Rao, Weihao; Zhang, Yuejun; Chen, Fa-Jie; Shi, Bing-Feng Angewandte Chemie - International Edition, 2013 , vol. 52, # 51 p. 13588 - 13592 Angew. Chem., 2013 , vol. 125, # 51 p. 13833 - 13837,5

~96%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Al-Farhan, Khalid; Ghazzali, Mohamed; Al-Hazimi, Hassan M.A.; El-Faham, Ayman; Reedijk, Jan Journal of Molecular Structure, 2011 , vol. 994, # 1-3 p. 269 - 275

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: Uraguchi, Daisuke; Kinoshita, Natsuko; Ooi, Takashi Journal of the American Chemical Society, 2010 , vol. 132, # 35 p. 12240 - 12242

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: El-Zahabi, Mohamed A.; Gad, Laila M.; Bamanie, Faida H.; Al-Marzooki, Zohair Medicinal Chemistry Research, 2012 , vol. 21, # 1 p. 75 - 84

~%

pht-ala-oh Structure

pht-ala-oh

CAS#:4192-28-3

Learn More
Literature: El-Zahabi, Mohamed A.; Gad, Laila M.; Bamanie, Faida H.; Al-Marzooki, Zohair Medicinal Chemistry Research, 2012 , vol. 21, # 1 p. 75 - 84

 pht-ala-ohBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of TNFalpha production in LPS-induced mouse peritoneal macrophages at 50 u...
Source: ChEMBL
Target: Peritoneal macrophage cell
External Id: CHEMBL3583655
Name: Antiproliferative activity against human MDA-MB-435 cells at 25 ug/ml after 48 hrs by...
Source: ChEMBL
Target: MDA-MB-435
External Id: CHEMBL2433014
Name: Antiproliferative activity against human HCT8 cells at 25 ug/ml after 48 hrs by MTT a...
Source: ChEMBL
Target: HCT-8
External Id: CHEMBL2433013
Name: Antiproliferative activity against human SF295 cells at 25 ug/ml after 48 hrs by MTT ...
Source: ChEMBL
Target: SF-295
External Id: CHEMBL2433012
Name: Immunomodulatory activity in BALB/c mouse splenocytes assessed as inhibition of LPS-i...
Source: ChEMBL
Target: Splenocyte
External Id: CHEMBL2433019
Name: Immunomodulatory activity in BALB/c mouse splenocytes assessed as inhibition of LPS-i...
Source: ChEMBL
Target: Splenocyte
External Id: CHEMBL2433018
Name: Inhibition of IL-1beta production in LPS-induced mouse peritoneal macrophages at 50 u...
Source: ChEMBL
Target: Peritoneal macrophage cell
External Id: CHEMBL3583656
Name: Antiinflammatory activity in carrageenan-induced air pouch mouse model assessed as in...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL2433021
Name: Cytotoxicity against BALB/c mouse splenocytes assessed as highest nontoxic concentrat...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2433020
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

N-Phth-Ala-OH
OZWUITKBAWTEAQ-UHFFFAOYSA
N-Pht-L-Ala
Phthaloyl-L-alanine
PHT-ALA-OH
N-phthaloylalanine
(2S)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
N-phthaloyl-L-alanine
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
PhtN-L-Ala-OH

 pht-ala-oh | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the storage conditions for (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Storage conditions for (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid: Store at 0°C.
Q: What is the molecular formula of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Molecular formula of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is C11H9NO4.
Q: What is the boiling point of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Boiling point of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is 407.9±28.0 °C at 760 mmHg.
Q: What English synonyms does (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid have?
A: English synonyms of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid: N-Phth-Ala-OH, OZWUITKBAWTEAQ-UHFFFAOYSA, N-Pht-L-Ala, Phthaloyl-L-alanine, PHT-ALA-OH, N-phthaloylalanine, (2S)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid, N-phthaloyl-L-alanine, 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid, PhtN-L-Ala-OH.
Q: What is the safety information for (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Safety information for (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid: 45.
Q: What is the LogP of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: LogP of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is 1.54.
Q: What are the upstream materials of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Related upstream materials(CAS) of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid: 85-44-9;56-41-7;22509-74-6;42406-36-0;338-69-2;1074-82-4.
Q: What is the polar surface area (PSA) of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Polar surface area (PSA) of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is 74.68000.
Q: What is the CAS number of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: CAS number of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is 4192-28-3.
Q: What is the melting point of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid?
A: Melting point of (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid is 139 - 141ºC.

 pht-ala-ohfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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