VU 0422288
Modify Date: 2024-01-10 11:52:38
VU 0422288 structure
|
Common Name | VU 0422288 | ||
|---|---|---|---|---|
| CAS Number | 1630936-95-6 | Molecular Weight | 360.194 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 422.6±45.0 °C at 760 mmHg | |
| Molecular Formula | C17H11Cl2N3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 209.4±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of VU 0422288VU0422288 is a potent, selective, CNS-penetrant pan-Group III mGlu positive allosteric modulator with IC50 of 110/146/130 nM for mGlu8/7/4, respectively, displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6). |
| Name | ML396 |
|---|---|
| Synonym | More Synonyms |
| Description | VU0422288 is a potent, selective, CNS-penetrant pan-Group III mGlu positive allosteric modulator with IC50 of 110/146/130 nM for mGlu8/7/4, respectively, displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6). |
|---|---|
| References | References 1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. View Related Products by Target mGluR |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 422.6±45.0 °C at 760 mmHg |
| Molecular Formula | C17H11Cl2N3O2 |
| Molecular Weight | 360.194 |
| Flash Point | 209.4±28.7 °C |
| Exact Mass | 359.022827 |
| LogP | 3.51 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.671 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| ML396 |
| N-(3-Chloro-4-((5-chloropyridin-2-yl)oxy)phenyl)picolinamide |
| 2-Pyridinecarboxamide, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]- |
| N-{3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl}-2-pyridinecarboxamide |
| MFCD28411626 |
| VU0422288 |