Didesethyl Chloroquine

Modify Date: 2024-01-01 22:14:13

Didesethyl Chloroquine Structure
Didesethyl Chloroquine structure
Common Name Didesethyl Chloroquine
CAS Number 4298-14-0 Molecular Weight 263.76600
Density 1.208g/cm3 Boiling Point 441.4ºC at 760 mmHg
Molecular Formula C14H18ClN3 Melting Point 139-141ºC
MSDS N/A Flash Point 220.8ºC

 Use of Didesethyl Chloroquine


Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].

 Names

Name Didesethyl Chloroquine
Synonym More Synonyms

 Didesethyl Chloroquine Biological Activity

Description Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].
Related Catalog
References

[1]. Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7.

[2]. Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6.

 Chemical & Physical Properties

Density 1.208g/cm3
Boiling Point 441.4ºC at 760 mmHg
Melting Point 139-141ºC
Molecular Formula C14H18ClN3
Molecular Weight 263.76600
Flash Point 220.8ºC
Exact Mass 263.11900
PSA 50.94000
LogP 4.20080
Index of Refraction 1.64
Storage condition 20°C

 Safety Information

Hazard Codes Xn
HS Code 2933499090

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-N-(7-chloroquinolin-4-yl)pentane-1,4-diamine
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