N6-Succinyl Adenosine

Modify Date: 2024-01-11 16:33:57

N6-Succinyl Adenosine Structure
N6-Succinyl Adenosine structure
Common Name N6-Succinyl Adenosine
CAS Number 4542-23-8 Molecular Weight 383.31300
Density 2.02g/cm3 Boiling Point 816.4ºC at 760mmHg
Molecular Formula C14H17N5O8 Melting Point N/A
MSDS N/A Flash Point 447.6ºC

 Use of N6-Succinyl Adenosine


Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].

 Names

Name succinyladenosine
Synonym More Synonyms

 N6-Succinyl Adenosine Biological Activity

Description Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100–500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL[1].
References

[1]. J Krijt, et al. Identification and Determination of Succinyladenosine in Human Cerebrospinal Fluid . J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):53-8.

 Chemical & Physical Properties

Density 2.02g/cm3
Boiling Point 816.4ºC at 760mmHg
Molecular Formula C14H17N5O8
Molecular Weight 383.31300
Flash Point 447.6ºC
Exact Mass 383.10800
PSA 200.15000
Storage condition -20°C

 Synthetic Route

 Synonyms

(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
N6-Succinyl Adenosine