NSC 15364
NSC 15364 structure
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Common Name | NSC 15364 | ||
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| CAS Number | 4550-72-5 | Molecular Weight | 242.277 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 381.4±27.0 °C at 760 mmHg | |
| Molecular Formula | C13H14N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 184.5±23.7 °C | |
Use of NSC 15364NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. |
| Name | 1,3-bis(4-aminophenyl)urea |
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| Synonym | More Synonyms |
| Description | NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. |
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| Related Catalog | |
| In Vitro | Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 381.4±27.0 °C at 760 mmHg |
| Molecular Formula | C13H14N4O |
| Molecular Weight | 242.277 |
| Flash Point | 184.5±23.7 °C |
| Exact Mass | 242.116760 |
| PSA | 93.17000 |
| LogP | -0.50 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.785 |
| Storage condition | -20℃ |
| HS Code | 2924299090 |
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~96%
NSC 15364 CAS#:4550-72-5 |
| Literature: Rodriguez, Fernando; Rozas, Isabel; Kaiser, Marcel; Brun, Reto; Nguyen, Binh; Wilson, W. David; Garcia, Rory Nelson; Dardonville, Christophe Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 909 - 923 |
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~73%
NSC 15364 CAS#:4550-72-5 |
| Literature: Khan, S. Rehman; Gilani; Inayat, Asma; Waheed, Shaheena Pakistan Journal of Scientific and Industrial Research, 2006 , vol. 49, # 5 p. 319 - 323 |
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NSC 15364 CAS#:4550-72-5 |
| Literature: Turner, William R.; Werbel, Leslie M. Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1728 - 1740 |
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NSC 15364 CAS#:4550-72-5 |
| Literature: Uno, Masaharu; Koma, Yosuke; Ban, Hyun Seung; Nakamura, Hiroyuki Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 16 p. 5169 - 5173 |
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NSC 15364 CAS#:4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
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NSC 15364 CAS#:4550-72-5 |
| Literature: Soloduschenkow et al. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1957 , vol. 30, p. 1361,1365; engl.Ausg.S.1430,1432 |
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~%
NSC 15364 CAS#:4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
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~%
NSC 15364 CAS#:4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
CAS#:25849-26-7| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
Source: 24386
Target: N/A
External Id: Sarm1 TIR NADase inhibitors
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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| 1,3-Bis(p-aminophenyl)urea |
| N,N'-Bis(4-aminophenyl)urea |
| 1,3-bis-(4-aminophenyl)urea |
| 1,3-Bis(4-aminophenyl)urea |
| 4,4'-diaminodiphenylurea |
| Carbanilide,4'-diamino |
| NSC 15364 |