Campesterol

Modify Date: 2024-01-02 20:18:33

Campesterol Structure
Campesterol structure
 Common Name Campesterol
CAS Number 474-62-4 Molecular Weight 400.680
Density 1.0±0.1 g/cm3 Boiling Point 489.5±14.0 °C at 760 mmHg
Molecular Formula C28H48O Melting Point 156-160ºC
MSDS Chinese USA Flash Point 214.3±12.4 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Campesterol


Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

 Names

Name campesterol
Synonym More Synonyms

 Campesterol Biological Activity

Description Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.
Related Catalog
In Vitro Campesterol shows a weak cytotoxicity in non-proliferating human umbilical vein endothelial cells (HUVECs). Within the non-cytotoxic concentration range, campesterol significantly inhibits the bFGF-induced proliferation and tube formation of HUVECs in a concentration-dependent manner, while it does not affect the motility of HUVECs. 50 μg/mL of campesterol decreases the cell viability up to about 56% of control(IC50 of over 50 μg/mL)[1].
In Vivo Campesterol effectively disrupts the bFGF-induced neovascularization in chick chorioallantoic membrane (CAM) in vivo[1].
Cell Assay The effect of campesterol on the viable cell number was assessed by XTT assay. HUVECs were treated with various concentrations (10, 20, 30, 40 and 50 μg/mL) of campesterol and incubated at 37 °C in a humidified incubator for 24 h, a XTT working solution was added to each well. The cells were incubated at 37 °C for 2 h and the optical density was measured using a microplate reader at 450 nm[1].
References

[1]. Choi JM, et al. Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities. Phytother Res. 2007 Oct;21(10):954-9.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 489.5±14.0 °C at 760 mmHg
Melting Point 156-160ºC
Molecular Formula C28H48O
Molecular Weight 400.680
Flash Point 214.3±12.4 °C
Exact Mass 400.370514
PSA 20.23000
LogP 10.20
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.522
Storage condition -20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;T: Toxic;
Risk Phrases R20/21/22
Safety Phrases 26-36-45-36/37/39-23
RIDADR UN 1888 6.1/PG 3

 Synthetic Route

 Articles62

More Articles
Phytochemical Characterization of Veronica officinalis L., V. teucrium L. and V. orchidea Crantz from Romania and Their Antioxidant and Antimicrobial Properties.

Int. J. Mol. Sci. 16 , 21109-27, (2015)

Aerial parts of Veronica species are used in Romanian traditional medicine for the treatment of various conditions like kidney diseases, cough, and catarrh, and are known for their wound-healing prope...

Sterol Composition in Infant Formulas and Estimated Intake.

J. Agric. Food Chem. 63 , 7245-51, (2015)

Sterol contents in infant formulas (IFs) from the European market were determined, and their intakes by infants between 0 and 6 months were evaluated. Total animal sterols (mg/100 mL) ranged from 1.71...

On-line liquid chromatography-gas chromatography: A novel approach for the analysis of phytosterol oxidation products in enriched foods.

J. Chromatogr. A. 1396 , 98-108, (2015)

A novel methodology for the automated qualitative and quantitative determination of phytosterol oxidation products in enriched foods via on-line liquid chromatography-gas chromatography (LC-GC) was es...

 Synonyms

Ergost-5-en-3β-ol, (24R)-
(24R)-Ergost-5-en-3b-ol
(24R)-5-Ergosten-3β-ol
EINECS 207-484-4
(3β,24R)-Ergost-5-en-3-ol
(24R)-5-Ergosten-3-β-ol
(3b,24R)-Ergost-5-en-3-ol
MFCD00010475
(24R)-Ergost-5-en-3β-ol
(24R)-5-Ergosten-3b-ol
Ergost-5-en-3-ol, (3β)-
Ergost-5-en-3β-ol
Campesterol
(24R)-Ergost-5-en-3-β-ol
(3β)-Ergost-5-en-3-ol
Ergost-5-en-3-β-ol
Ergost-5-en-3-ol, (3β,24R)-
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Chemsrc provides Campesterol(CAS#:474-62-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Campesterol are included as well.>> amp version: Campesterol

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