Chalinasterol

Modify Date: 2026-07-10 10:20:56

Chalinasterol Structure
Chalinasterol structure
Common Name Chalinasterol
CAS Number 474-63-5 Molecular Weight 398.66400
Density 0.98g/cm3 Boiling Point 490.3ºC at 760mmHg
Molecular Formula C28H46O Melting Point N/A
MSDS N/A Flash Point 213.8ºC

 Use of Chalinasterol


24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 24-methylenecholesterol
Synonym More Synonyms

 Chalinasterol Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].
Related Catalog
References

[1]. Tabas I, et al. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction. J Clin Invest. 1989 Dec;84(6):1713-21.

[2]. Sun Y, et al. Sterols from Mytilidae show anti-aging and neuroprotective effects via anti-oxidative activity. Int J Mol Sci. 2014 Nov 25;15(12):21660-73.

[3]. Chakrabarti P, et al. Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol. Insects. 2020 Oct 29;11(11):743.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 0.98g/cm3
Boiling Point 490.3ºC at 760mmHg
Molecular Formula C28H46O
Molecular Weight 398.66400
Flash Point 213.8ºC
Exact Mass 398.35500
PSA 20.23000
LogP 7.55480
Vapour Pressure 1.14E-11mmHg at 25°C
Index of Refraction 1.528
InChIKey INDVLXYUCBVVKW-PXBBAZSNSA-N
SMILES C=C(CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 ChalinasterolBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 16 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993373
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL4400901
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 128 ug/mL by m...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993370
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 32 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993372
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 64 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993371
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by microplate ala...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL989790
Name: Cytotoxicity against african green monkey Vero cells
Source: ChEMBL
Target: Vero
External Id: CHEMBL941144
Name: Selectivity index, ratio of IC50 for against african green monkey VERO cells to MIC f...
Source: ChEMBL
Target: N/A
External Id: CHEMBL989792
Name: Cytotoxicity against african green monkey Vero cells
Source: ChEMBL
Target: Vero
External Id: CHEMBL989791
Name: Antifungal activity against Saccharomyces cerevisiae RS 322YK (rad 52Y) assessed as D...
Source: ChEMBL
Target: Saccharomyces cerevisiae
External Id: CHEMBL941143
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

24-methylencholesterol
Chalinasterol

 Chalinasterol | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of 24-methylenecholesterol?
A: LogP of 24-methylenecholesterol is 7.55480.
Q: What is the English name of 24-methylenecholesterol?
A: The English name of 24-methylenecholesterol is 24-methylenecholesterol.
Q: What are the downstream products of 24-methylenecholesterol?
A: Related downstream products(CAS) of 24-methylenecholesterol: 474-62-4;474-60-2;50-00-0;57-88-5;313-04-2;2364-23-0.
Q: What are the upstream materials of 24-methylenecholesterol?
A: Related upstream materials(CAS) of 24-methylenecholesterol: 17752-16-8;1779-49-3;68844-31-5;2065-66-9;83-48-7;53906-49-3;121077-68-7;287471-28-7.
Q: What is the boiling point of 24-methylenecholesterol?
A: Boiling point of 24-methylenecholesterol is 490.3ºC at 760mmHg.
Q: What is the molecular weight of 24-methylenecholesterol?
A: Molecular weight of 24-methylenecholesterol is 398.66400.
Q: What is the polar surface area (PSA) of 24-methylenecholesterol?
A: Polar surface area (PSA) of 24-methylenecholesterol is 20.23000.
Q: What is the CAS number of 24-methylenecholesterol?
A: CAS number of 24-methylenecholesterol is 474-63-5.
Q: What is the InChIKey of 24-methylenecholesterol?
A: InChIKey of 24-methylenecholesterol is INDVLXYUCBVVKW-PXBBAZSNSA-N.
Q: What is the molecular formula of 24-methylenecholesterol?
A: Molecular formula of 24-methylenecholesterol is C28H46O.

 Chalinasterolfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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