Chalinasterol

Modify Date: 2025-08-26 12:44:37

Chalinasterol Structure
Chalinasterol structure
Common Name Chalinasterol
CAS Number 474-63-5 Molecular Weight 398.66400
Density 0.98g/cm3 Boiling Point 490.3ºC at 760mmHg
Molecular Formula C28H46O Melting Point N/A
MSDS N/A Flash Point 213.8ºC

 Use of Chalinasterol


24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].

 Names

Name 24-methylenecholesterol
Synonym More Synonyms

 Chalinasterol Biological Activity

Description 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].
Related Catalog
References

[1]. Tabas I, et al. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction. J Clin Invest. 1989 Dec;84(6):1713-21.

[2]. Sun Y, et al. Sterols from Mytilidae show anti-aging and neuroprotective effects via anti-oxidative activity. Int J Mol Sci. 2014 Nov 25;15(12):21660-73.

[3]. Chakrabarti P, et al. Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol. Insects. 2020 Oct 29;11(11):743.

 Chemical & Physical Properties

Density 0.98g/cm3
Boiling Point 490.3ºC at 760mmHg
Molecular Formula C28H46O
Molecular Weight 398.66400
Flash Point 213.8ºC
Exact Mass 398.35500
PSA 20.23000
LogP 7.55480
Vapour Pressure 1.14E-11mmHg at 25°C
Index of Refraction 1.528
InChIKey INDVLXYUCBVVKW-PXBBAZSNSA-N
SMILES C=C(CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C

 Synthetic Route

 ChalinasterolBioassay

View more

Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 16 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993373
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL4400901
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 128 ug/mL by m...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993370
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 32 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993372
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 64 ug/mL by mi...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL993371
Name: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by microplate ala...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL989790
Name: Cytotoxicity against african green monkey Vero cells
Source: ChEMBL
Target: Vero
External Id: CHEMBL941144
Name: Selectivity index, ratio of IC50 for against african green monkey VERO cells to MIC f...
Source: ChEMBL
Target: N/A
External Id: CHEMBL989792
Name: Cytotoxicity against african green monkey Vero cells
Source: ChEMBL
Target: Vero
External Id: CHEMBL989791
Name: Antifungal activity against Saccharomyces cerevisiae RS 322YK (rad 52Y) assessed as D...
Source: ChEMBL
Target: Saccharomyces cerevisiae
External Id: CHEMBL941143
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 Synonyms

24-methylencholesterol
Chalinasterol
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