2,6-Dichloropyrazine

2,6-Dichloropyrazine Structure
2,6-Dichloropyrazine structure
Common Name 2,6-Dichloropyrazine
CAS Number 4774-14-5 Molecular Weight 148.97
Density 1.5±0.1 g/cm3 Boiling Point 187.5±35.0 °C at 760 mmHg
Molecular Formula C4H2Cl2N2 Melting Point 55-58 °C(lit.)
MSDS Chinese USA Flash Point 83.8±11.5 °C
Symbol GHS07
GHS07
Signal Word Warning

Syntheses and properties of two-dimensional, dicationic nonlinear optical chromophores based on pyrazinyl cores.

J. Org. Chem. 75(24) , 8550-63, (2010)

Six new dicationic 2D nonlinear optical (NLO) chromophores with pyrazinyl-pyridinium electron acceptors have been synthesized by nucleophilic substitutions of 2,6-dichloropyrazine with pyridyl derivatives. These compounds have been characterized as their PF(6...

Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.

Bioorg. Med. Chem. 21(21) , 6732-41, (2013)

Dicationic 2,6-diphenylpyrazines, aza-analogues and prodrugs were synthesized; evaluated for DNA affinity, activity against Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.) in vitro, efficacy in T. b. r. STIB900 acute and T. b. bruc...

Synthesis of oxacalixarenes incorporating nitrogen heterocycles: evidence for thermodynamic control.

Org. Lett. 8 , 2755, (2006)

[structure: see text] Oxacalix[2]arene[2]hetarenes are formed in a single step by cyclooligomerization of meta-diphenols with meta-dichlorinated azaheterocycles. The high selectivity for cyclic tetramer formation results from thermodynamic product control. Ma...

Carboxylic acid functionalized ortho-linked oxacalix[2]benzene[2]pyrazine: synthesis, structure, hydrogen bond and metal directed self-assembly.

Dalton Trans. 41(18) , 5625-33, (2012)

Cyclooligomerization of 2,6-dichloropyrazine 4 and benzyl 2,3-dihydroxybenzoate 5 under microwave irradiation resulted in a racemic pair of ester functionalized ortho-linked oxacalix[2]benzene[2]pyrazine 6, which was further transformed to the corresponding r...