Benzyl-PEG4-MS

Modify Date: 2024-01-29 14:23:11

Benzyl-PEG4-MS Structure
Benzyl-PEG4-MS structure
Common Name Benzyl-PEG4-MS
CAS Number 477781-69-4 Molecular Weight 362.438
Density 1.2±0.1 g/cm3 Boiling Point 497.1±40.0 °C at 760 mmHg
Molecular Formula C16H26O7S Melting Point N/A
MSDS N/A Flash Point 254.5±27.3 °C

 Use of Benzyl-PEG4-MS


Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate
Synonym More Synonyms

 Benzyl-PEG4-MS Biological Activity

Description Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 497.1±40.0 °C at 760 mmHg
Molecular Formula C16H26O7S
Molecular Weight 362.438
Flash Point 254.5±27.3 °C
Exact Mass 362.139923
LogP 0.42
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.502

 Synonyms

1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate
2,5,8,11-Tetraoxatridecan-13-ol, 1-phenyl-, methanesulfonate
Benzyl-PEG4-MS
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